The RNA-binding protein IGF2BP1 has emerged as a key regulator of cancer hallmarks, influencing tumour proliferation, metastasis, immune evasion, and...
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The RNA-binding protein IGF2BP1 has emerged as a key regulator of cancer hallmarks, influencing tumour proliferation, metastasis, immune evasion, and resistance to cell death. As an m6A reader, IGF2BP1 binds to methylated mRNA, stabilising oncogenic transcripts and promoting cancer progression. Its role in regulating gene expression at the post-transcriptional level has positioned IGF2BP1 as a [...]
The RNA-binding protein IGF2BP1 has emerged as a key regulator of cancer hallmarks, influencing tumour proliferation, metastasis, immune evasion, and...
Breast cancer, particularly triple-negative breast cancer (TNBC), remains a leading cause of cancer-related mortality due to its aggressive nature and...
The innate immune system is the body's first line of defense against pathogens and foreign substances. An essential component of this system are...
Fusion genes, arising from abnormal chromosomal rearrangements, are gaining recognition as pivotal players in cancer development. These genetic...
Inflammatory mediators like cytokines and chemokines play a key role in driving age-related and postmenopausal breast cancer progression and immune...
When cancer spreads from a primary tumour to new sites throughout the body, it undergoes changes that increase its genetic complexity. A new study...
Gliomas are among the deadliest brain tumors, with limited treatment options and poor survival rates. Scientists from China identified FAM111B, a...
What if we told you that not all cancer cells in a tumour are the same-and that's exactly why some treatments fail? A groundbreaking AI tool called...
New AI tool, maps cancer cell diversity into five key types, unlocking the potential for personalized treatment and improved outcomes in breast...
Melanoma, one of the deadliest forms of skin cancer, affects an estimated 330,000 people worldwide each year and causes nearly 60,000 deaths...