The tumor microenvironment (TME) represents a highly complex system that encompasses cellular components (such as cancer cells, stromal cells, and...
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T cell senescence occurs in the TME, affecting cancer prognosis and immunotherapy efficacy. The TME induces T cell senescence through multiple pathways, including persistent stimulation by tumor-associated antigens, metabolic pathway alterations, activation of chronic inflammatory responses, proliferation of immunosuppressive cells, and T cell damage caused by tumor radiotherapy and chemotherapy.
The tumor microenvironment (TME) represents a highly complex system that encompasses cellular components (such as cancer cells, stromal cells, and...
Chemotherapy used to target and kill bladder cancer cells may trigger an inflammatory response that ultimately may make the cancer more resistant to...
Chemotherapy used to target and kill bladder cancer cells may trigger an inflammatory response that ultimately may make the cancer more resistant to...
Head and neck squamous cell carcinomas (HNSCC) are a group of cancers that affect cells in and around our mouth and nose.
Greek researchers led by Dr. Ioannis Mountzios report breakthrough results in a lung cancer study. Credit: Harrygouvas / Wikimedia Commons / CC BY-SA...
Pittsburgh: A new study has found that patients with melanoma and non-small cell lung cancer who consumed high levels of sucralose-a widely used...
A new study from Houston Methodist reveals a surprising twist in the fight against bladder cancer: a type of cancer cell death triggered by...
A new study from Houston Methodist reveals a surprising twist in the fight against bladder cancer: a type of cancer cell death triggered by...
Immune-inflammatory skin diseases (e.g., psoriasis, atopic dermatitis) involve dysregulation of CD4+ T-cell subsets (Th1/Th2/Th17/Treg) and cytokine...
In a wholly new approach to cancer treatment, Northwestern University biomedical engineers have doubled the effectiveness of chemotherapy in animal...