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  - WN.COM - Health - Yesterday 13:14

Scripps Research clinical trial fights cancer with novel on-off switch

Generally, fighting cancer is about delivering a relentless attack on the spreading disease, but a new approach explores the possible benefits of toggling therapy off and on like a light switch, allowing oncologists to more precisely control drug action and potential side effects. A new trial just getting underway at Scripps Research Institute in La Jolla is using two novel medications in combination to create a sort of failsafe version of the “CAR” T-cell therapy that has proven effective at driving blood cancers such as lymphoma and leukemia into remission. Concerns over potential toxicity and loss of potency have so far limited the applicability of these targeted white blood...

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