CRISPR-Cas9 enables researchers to make precise and targeted edits in the genome to determine gene function. For this, scientists use guide RNAs,...
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CRISPR-Cas9 enables researchers to make precise and targeted edits in the genome to determine gene function. For this, scientists use guide RNAs, which are short stretches of RNA sequences that lead the Cas9 enzyme to its target region of the genome. The enzyme causes double-stranded DNA breaks, which consequently turns off gene function when a cell cannot correctly repair the break. In 2017, Jesse Boehm, a genomics scientist at the Broad Institute of MIT and Harvard, and his team had used multiple guide RNAs to perform a genome-wide screen in cancer cells lines from 1,000s of patients.1 They used the CRISPR-Cas9 system to target each gene and identified many “cancer dependencies”—genes...
CRISPR-Cas9 enables researchers to make precise and targeted edits in the genome to determine gene function. For this, scientists use guide RNAs,...
New research has found a novel target with therapeutic potential for metastatic eye melanoma, an aggressive eye cancer, with implications for a range...
Diagnoses for serious diseases can sometimes come at a high cost, causing health issues to only be discovered when they are too late to be...
Diagnoses for serious diseases can sometimes come at a high cost, causing health issues to only be discovered when they are too late to be...
CRISPR is revolutionizing medicine by enabling precise DNA edits, treating genetic diseases like sickle cell anemia and beta-thalassemia, and...
Meta has improved its video editing app Edits with several new features to enhance the capabilities of content creators. The first feature is a...
Nine months after the state-of-the-art $10 million cancer treatment machine arrived in Barbados, it is yet to be installed and commissioned at the...
CNN — In a long-sought first, researchers have sequenced the entire genome of an ancient Egyptian person, revealing unprecedented insight about...
CNN — In a long-sought first, researchers have sequenced the entire genome of an ancient Egyptian person, revealing unprecedented insight about...
A new international study suggests that ancient viral DNA embedded in our genome, which were long dismissed as genetic "junk", may actually play...