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  - WN.COM - Science - 27/Aug 19:32

Scientists achieve “striking” memory improvements by suppressing brain protein

A new study published in Nature Aging provides evidence that a single protein in the brain may play a central role in age-related memory loss—and that suppressing this protein could restore cognitive function in older animals. Researchers at the University of California, San Francisco found that increasing levels of a protein called ferritin light chain 1 (Ftl-1) in neurons impairs memory and synaptic function in young mice, while reducing its levels in aged mice rejuvenates brain function. Cognitive decline is a common feature of aging, even in the absence of disease. Past work has shown that this decline is not primarily caused by neuron death, but rather by changes in how neurons...

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