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  - WN.COM - Science - Aujourd'hui 05:02

3D Genome Rewiring Alters Gene Expression in Cancer

Despite spanning about three billion base pairs, the human genome is wrapped up tight in a highly organized fashion in the nucleus. This coordinated structure, in part, enables the cell to regulate gene expression. One of the ways that cells accomplish this is through enhancer elements. These sequences are sometimes tens to hundreds of thousands of base pairs away from the genes they regulate, but by binding to transcription factors and physically looping the DNA, they bring these molecules into contact with a gene’s promoter. In cancer, mutations and other genetic alterations can increase enhancer binding and subsequently drive gene expression.1 Although previous studies reported changes to...

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3D Genome Rewiring Alters Gene Expression in Cancer

wn.com - 05:02

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AI Tool Identifies Disease-Driving Promoter Mutations

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AI Tool Identifies Disease-Driving Promoter Mutations

wn.com - 05:02

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ESR1 Mutated Metastatic Breast Cancer Diagnostics Market to Grow to USD 92.9M by 2035

wn.com - 07:32

The ESR1 mutated metastatic breast cancer diagnostics market is valued at USD 64.61 million in 2025 and is slated to reach USD 92.92 million by 2035,...

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ESR1 Mutated Metastatic Breast Cancer Diagnostics Market to Grow to USD 92.9M by 2035

wn.com - 07:32

The ESR1 mutated metastatic breast cancer diagnostics market is valued at USD 64.61 million in 2025 and is slated to reach USD 92.92 million by 2035,...

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Life X DNA™ Methylation Testing Now Available Across Australia And New Zealand

wn.com - 02:41

DNA methylation tests examine chemical modifications on DNA that regulate gene expression without altering the genetic code. Services are available in...

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Life X DNA™ Methylation Testing Now Available Across Australia And New Zealand

wn.com - 02:41

DNA methylation tests examine chemical modifications on DNA that regulate gene expression without altering the genetic code. Services are available in...

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How Genetics Shape the Fate of Stomach Tumors

medindia.net - 21/Jun 20:54

Using next-generation DNA sequencing, researchers have discovered bfour gene mutations associated with the onset and progression of aggressive...

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How Genetics Shape the Fate of Stomach Tumors

medindia.net - 21/Jun 20:54

Using next-generation DNA sequencing, researchers have discovered bfour gene mutations associated with the onset and progression of aggressive...

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HPV drives tumour development in rare nasal cancers

oncologynews.com.au - 15/Jun 16:57

Human papillomavirus (HPV) can drive tumour development in some rare sinonasal squamous cell carcinomas (SNSCCs), according to a new comprehensive...

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