X

Vous n'êtes pas connecté

Rubriques :

  - WN.COM - Science - 15/Jul 05:22

Ancestry Bias Could Cause CRISPR Screens to Veer Off-target

CRISPR-Cas9 enables researchers to make precise and targeted edits in the genome to determine gene function. For this, scientists use guide RNAs, which are short stretches of RNA sequences that lead the Cas9 enzyme to its target region of the genome. The enzyme causes double-stranded DNA breaks, which consequently turns off gene function when a cell cannot correctly repair the break. In 2017, Jesse Boehm, a genomics scientist at the Broad Institute of MIT and Harvard, and his team had used multiple guide RNAs to perform a genome-wide screen in cancer cells lines from 1,000s of patients.1 They used the CRISPR-Cas9 system to target each gene and identified many “cancer dependencies”—genes...

Articles similaires

Sorry! Image not available at this time

Ancestry Bias Could Cause CRISPR Screens to Veer Off-target

wn.com - 15/Jul 05:22

CRISPR-Cas9 enables researchers to make precise and targeted edits in the genome to determine gene function. For this, scientists use guide RNAs,...

Sorry! Image not available at this time

New drug target for metastatic eye melanoma

oncologynews.com.au - 07/Jul 15:02

New research has found a novel target with therapeutic potential for metastatic eye melanoma, an aggressive eye cancer, with implications for a range...

Sorry! Image not available at this time

MIT Researchers Create Disease Scanner That Can Detect Cancer Cells

thecekodok.com - 07/Jul 10:38

Diagnoses for serious diseases can sometimes come at a high cost, causing health issues to only be discovered when they are too late to be...

Sorry! Image not available at this time

MIT Researchers Create Disease Scanner That Can Detect Cancer Cells

thecekodok.com - 07/Jul 10:38

Diagnoses for serious diseases can sometimes come at a high cost, causing health issues to only be discovered when they are too late to be...

Sorry! Image not available at this time

CRISPR Explained: How Gene Editing Is Reshaping Medicine

wn.com - 05/Jul 14:20

CRISPR is revolutionizing medicine by enabling precise DNA edits, treating genetic diseases like sickle cell anemia and beta-thalassemia, and...

Sorry! Image not available at this time

Study elucidates relationship between Type 2 diabetes and salivary enzyme gene

news.medical.net - 04/Jul 05:11

A new Cornell University study brings additional clarity to the relationship between Type 2 diabetes and genes that express a salivary enzyme that...

Sorry! Image not available at this time

Edits Updated With New Music, Keyframes, and Sound Effects

thecekodok.com - 11:13

Meta has improved its video editing app Edits with several new features to enhance the capabilities of content creators. The first feature is a...

Sorry! Image not available at this time

Ancient Egyptian man’s genome reveals his society’s cross-cultural ties

stabroeknews.com - 03/Jul 06:03

(Reuters) – DNA obtained from the remains of a man who lived in ancient Egypt around the time the first pyramids were built is providing...

Sorry! Image not available at this time

Ancient Egyptian man’s genome reveals his society’s cross-cultural ties

stabroeknews.com - 03/Jul 06:03

(Reuters) – DNA obtained from the remains of a man who lived in ancient Egypt around the time the first pyramids were built is providing...

Sorry! Image not available at this time

$10m cancer treatment machine still in storage

nationnews.com - 13/Jul 11:53

Nine months after the state-of-the-art $10 million cancer treatment machine arrived in Barbados, it is yet to be installed and commissioned at the...

Les derniers communiqués