A type of aggressive, treatment-resistant brain tumour has a distinct population of immune cells that support its growth, according to new research...

A gene called high mobility group A1 (HMGA1) may be the key that opens the door to the development of colon cancer, according to research led by...

A new case report was published in Volume 16 of Oncotarget on February 5, 2025, titled “Acquired RUFY1-RET rearrangement as a mechanism of...

This review highlights the critical role of ubiquitination in governing the functionality of cancer stem cells (CSCs), shedding light on potential...

Combining an existing small-molecule protein therapy called tumour necrosis factor-related apoptosis-inducing ligand (TRAIL) with focused ultrasound...

A new research paper was published in Oncotarget, Volume 16, on February 28, 2025, titled "Effect of TIMPs and their minimally engineered variants in...

Researchers from the Icahn School of Medicine at Mount Sinai in New York have discovered a novel approach to protecting insulin-producing beta cells...

Dana-Farber Cancer Institute researchers report that all nine patients in a clinical trial being treated for stage III or IV clear cell renal cell...

Changes to the intermediate filament (IF) protein, vimentin, were found to promote tumour growth by increasing cancer stemness in an oestrogen...

Scientists at Northwestern Medicine have discovered that blocking a protein called GATA6 in mice with colon cancer slowed down tumor growth and helped...