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Maroc Maroc - ONCOLOGYNEWS.COM.AU - A La Une - 15/12/2025 05:36

New research discovers dementia-linked protein’s role in DNA mistakes

New Houston Methodist research has revealed that a protein associated with neurodegenerative diseases such as dementia and amyotrophic lateral sclerosis (ALS) also plays a role in regulating DNA mismatch repair, a process essential for replicating genetic information and cell health. The finding could change how scientists understand both cancer and neurodegeneration. The study, published in Nucleic Acids Research, finds that the protein, ‘TDP43’, regulates genes that fix DNA mistakes. When this protein is lost or overproduced, these [...]

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