A recent study has revealed that certain medications used to treat type 2 diabetes may offer protection against dementia and Alzheimer’s disease...
Vous n'êtes pas connecté
People with type 2 diabetes who are treated with GLP-1 agonists have a decreased risk of developing dementia, according to a new study from Karolinska Institutet in Sweden published in the journal eClinicalMedicine. Drugs known as GLP-1 agonists or GLP-1 analogues have become increasingly popular in treating type 2 diabetes and obesity as they help control blood sugar, promote weight loss and protect the heart. People with type 2 diabetes have an increased risk of developing dementia and it’s been hypothesised that newer diabetes drugs such as GLP-1 agonists and DPP-4 inhibitors might have a protective effect. In the new register-based study, researchers followed more than 88,000 older individuals with type 2 diabetes for up to ten years. Using a study design called target trial emulation, which imitates a randomised clinical trial, they analysed the association between three diabetes drugs (GLP-1 agonists, DPP-4 inhibitors or sulfonylureas) and the risk of dementia. They found that patients who used GLP-1 agonists had a 30 per cent lower risk of developing dementia compared to those who used sulfonylureas, and a 23 per cent lower risk compared to those who used DPP-4 inhibitors. “This is important because it can help doctors make better decisions about which medicines to use for older patients with type 2 diabetes,” says lead author Bowen Tang, a PhD student in Sara Hägg’s research group at the Department of Medical Epidemiology and Biostatistics, Karolinska Institutet. “However, proper randomised trials are needed to establish with certainty that GLP-1 agonists reduce the risk of dementia.” The study was funded by the Swedish Research Council, Karolinska Institutet, the National Institute on Aging, the National Institutes of Health, and Riksbankens Jubileumsfond. There are no reported conflicts of interest.
A recent study has revealed that certain medications used to treat type 2 diabetes may offer protection against dementia and Alzheimer’s disease...
A new study has found that people with type 2 diabetes who have lower levels of diligence, or conscientiousness, may face a higher risk of developing...
When we discuss heart health for people with type 2 diabetes, the conversation often goes beyond the typical advice of improving diet and exercise. A...
When we discuss heart health for people with type 2 diabetes, the conversation often goes beyond the typical advice of improving diet and exercise. A...
THURSDAY, Sept. 19, 2024 -- A specific class of diabetes drug appears to lower people’s risk for dementia and Parkinson’s disease, a new study...
A recent study led by researchers from Monash University in Australia, in collaboration with scientists worldwide, looked into the link between blood...
Scientists from the University of Copenhagen have detected lipid biomarkers in children and teenagers with obesity that indicate an increased risk of...
WEDNESDAY, Sept. 18, 2024 -- For patients with type 2 diabetes, sodium-glucose cotransporter 2 inhibitor (SGLT2i) use is associated with reduced...
Researchers from the University of Liverpool have found that the weight-loss drug tirzepatide could significantly reduce the risk of developing type 2...
Researchers from the University of Liverpool have found that the weight-loss drug tirzepatide could significantly reduce the risk of developing type 2...