Maroc - ONCOLOGYNEWS.COM.AU - A La Une - 26/Mar 16:10

CRG-based classification model for IDH1-mutant gliomas

Glioma, the most common primary malignant tumour of the central nervous system, presents significant clinical challenges due to its pronounced intratumoural heterogeneity and poor prognosis. Notably, isocitrate dehydrogenase 1 (IDH1) mutations occur in over 70% of WHO grade II–III gliomas. While patients with IDH1-mutant gliomas generally have better survival outcomes than those with wild-type tumours, [...]